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China approves first-ever drug for acute mountain sickness prevention_我的网站

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一 |     Filmfare returned with the 6th edition of the Filmfare OTT Awards to honour the finest artistes, directors, storytellers, musicians and technicians from OTT series, web original films and short films. The grand awards ceremony, held on December 15, 2025, saw some of the best names take home the prestigious Black Lady. The Best Series Award went to Black Warrant while Paatal Lok bagged the Best Series, Critics' Award. Monika Panwar won in the Best Actor Series (Female): Drama category for her role in the spine-chilling Khauf while Jaideep Ahlawat won the Best Actor, Series (Male): Drama award for the gritty Paatal Lok. Barun Sobti and Sparsh Shrivastava were joint winners in the Best Actor Series (Male): Comedy category for Raat Jawaan Hai and Dupahiya, respectively. Ananya Panday bagged the Best Actor, Series (Female): Comedy award for for Call Me Bae. Here are the winners of Filmfare OTT Awards 2025, co-powered by Hyundai and Blenders Pride.     In This Article      BEST SERIESBEST DIRECTOR, SERIESBEST SERIES (CRITICS')BEST DIRECTOR: SERIES (CRITICS')BEST ACTOR, SERIES (MALE): DRAMABEST ACTOR (MALE), SERIES, CRITICS': DRAMABEST ACTOR, SERIES (FEMALE): DRAMABEST ACTOR (FEMALE), SERIES, CRITICS': DRAMABEST COMEDY (SERIES/SPECIALS)BEST ACTOR, SERIES (MALE): COMEDYBEST ACTOR, SERIES (FEMALE): COMEDYBEST SUPPORTING ACTOR, SERIES (MALE): DRAMABEST SUPPORTING ACTOR, SERIES (FEMALE ): DRAMABEST SUPPORTING ACTOR, SERIES (MALE): COMEDYBEST SUPPORTING ACTOR, SERIES (FEMALE): COMEDYBEST (NON FICTION) ORIGINAL (SERIES/ SPECIAL)BEST FILM, WEB ORIGINALBEST DIRECTOR, WEB ORIGINAL FILMBEST WEB ORIGINAL FILM: CRITICS'BEST ACTOR, WEB ORIGINAL FILM (MALE)BEST ACTOR, WEB ORIGINAL FILM (FEMALE)BEST ACTOR (MALE) CRITICS' WEB ORIGINAL FILMBEST ACTOR (FEMALE) CRITICS' WEB ORIGINAL FILMBEST SUPPORTING ACTOR, WEB ORIGINAL FILM (MALE)BEST SUPPORTING ACTOR, WEB ORIGINAL FILM (FEMALE)BEST STORY, SERIESBEST ORIGINAL SCREENPLAY, SERIESBEST ADAPTED SCREENPLAY, SERIESBEST DIALOGUE, SERIESBEST CINEMATOGRAPHER, SERIESBEST PRODUCTION DESIGN, SERIESBEST EDITING, SERIESBEST COSTUME DESIGN, SERIESBEST BACKGROUND MUSIC, SERIESBEST VFX, SERIESBEST SOUND DESIGN, SERIESBEST MUSIC ALBUM, SERIESBEST STORY (WEB ORIGINAL FILM)BEST ORIGINAL SCREENPLAY (WEB ORIGINAL FILM)BEST DIALOGUE (WEB ORIGINAL FILM)BEST CINEMATOGRAPHER (WEB ORIGINAL FILM)BEST PRODUCTION DESIGN (WEB ORIGINAL FILM)BEST EDITING (WEB ORIGINAL FILM)BEST BACKGROUND MUSIC (WEB ORIGINAL FILM)BEST SOUND DESIGN (WEB ORIGINAL FILM)BEST MUSIC ALBUM (WEB ORIGINAL FILM)BEST DEBUT DIRECTOR, SERIESBREAKTHROUGH PERFORMANCE BY A NEWCOMER (MALE), SERIESBREAKTHROUGH PERFORMANCE BY A NEWCOMER (FEMALE), SERIESBEST DEBUT DIRECTOR, WEB ORIGINAL FILMBREAKTHROUGH PERFORMANCE BY NEWCOMER (MALE), WEB ORIGINAL FILMBREAKTHROUGH PERFORMANCE BY NEWCOMER (FEMALE), WEB ORIGINAL FILMBEST SHORT FILM (PEOPLE'S CHOICE)BEST ACTOR (FEMALE), SHORT FILMBEST ACTOR (MALE), SHORT FILMBEST SHORT FILM (FICTION)BEST SHORT FILM (NON-FICTION OR DOCUMENTARY)BEST DIRECTOR, SHORT FILMBEST SERIES     BLACK WARRANT     BEST DIRECTOR, SERIES     VIKRAMADITYA MOTWANE, SATYANSHU SINGH, ARKESH AJAY, AMBIECKA PANDIT AND ROHIN RAVEENDRAN (BLACK WARRANT)     BEST SERIES (CRITICS')     PAATAL LOK SEASON 2     BEST DIRECTOR: SERIES (CRITICS')     ANUBHAV SINHA (IC 814: THE KANDAHAR HIJACK)     NAGESH KUKUNOOR (THE HUNT: THE RAJIV GANDHI ASSASSINATION CASE)     BEST ACTOR, SERIES (MALE): DRAMA     JAIDEEP AHLAWAT (PAATAL LOK SEASON 2)     BEST ACTOR (MALE), SERIES, CRITICS': DRAMA     ZAHAN KAPOOR (BLACK WARRANT)     BEST ACTOR, SERIES (FEMALE): DRAMA     MONIKA PANWAR (KHAUF)     BEST ACTOR (FEMALE), SERIES, CRITICS': DRAMA     RASIKA DUGAL (SHEKHAR HOME)     BEST COMEDY (SERIES/SPECIALS)     RAAT JAWAAN HAI (SUMEET VYAS)     BEST ACTOR, SERIES (MALE): COMEDY     BARUN SOBTI (RAAT JAWAAN HAI) SPARSH SHRIVASTAVA (DUPAHIYA)     BEST ACTOR, SERIES (FEMALE): COMEDY     ANANYA PANDAY (CALL ME BAE)     BEST SUPPORTING ACTOR, SERIES (MALE): DRAMA     RAHUL BHAT (BLACK WARRANT)     BEST SUPPORTING ACTOR, SERIES (FEMALE ): DRAMA     TILLOTAMA SHOME (PAATAL LOK- SEASON 2)     BEST SUPPORTING ACTOR, SERIES (MALE): COMEDY     VINAY PATHAK (GRAM CHIKITSALAY)     BEST SUPPORTING ACTOR, SERIES (FEMALE): COMEDY     RENUKA SHAHANE (DUPAHIYA)     BEST (NON FICTION) ORIGINAL (SERIES/ SPECIAL)     ANGRY YOUNG MEN (NAMRATA RAO)     BEST FILM, WEB ORIGINAL     GIRLS WILL BE GIRLS     BEST DIRECTOR, WEB ORIGINAL FILM     SHUCHI TALATI (GIRLS WILL BE GIRLS)     BEST WEB ORIGINAL FILM: CRITICS'     BOMAN IRANI (THE MEHTA BOYS)     BEST ACTOR, WEB ORIGINAL FILM (MALE)     ABHISHEK BANERJEE (STOLEN)     BEST ACTOR, WEB ORIGINAL FILM (FEMALE)     SANYA MALHOTRA (MRS)     BEST ACTOR (MALE) CRITICS' WEB ORIGINAL FILM     VIKRANT MASSEY (SECTOR 36)     BEST ACTOR (FEMALE) CRITICS' WEB ORIGINAL FILM     PREETI PANIGRAHI (GIRLS WILL BE GIRLS) 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Medicine File photo: VCG
    Medicine File photo: VCG
China has granted marketing approval of its first drug for the prevention of acute mountain sickness, filling the long-standing gap in the domestic market where no such medications had been available, Science and Technology Daily reported on Tuesday.
The National Medical Products Administration (NMPA) has approved the marketing of acetazolamide sustained-release capsules, the report said. As the first specialized drug in China indicated for preventing of acute mountain sickness, its approval marks the end of the country's lack of dedicated preventive treatment for altitude illness. 
By inhibiting the activity of carbonic anhydrase, acetazolamide promotes the renal excretion of bicarbonate, corrects respiratory alkalosis caused by hypoxia at high altitudes, thereby regulating acid-base balance, optimizing respiratory status, elevating blood oxygen levels, and reducing the risk of onset at the source. 
In contrast to health products that only provide auxiliary regulatory effects, this medication has been validated through stringent clinical trials and stands as a specialized drug approved by the NMPA with a clear indication for prevention, said the report.
Led by principal investigator is Luobu Gesang, a deputy dean of the People's Hospital of Xizang Autonomous Region, the clinical trial was designed by his team and has yielded critical evidence to inform prevention strategies for altitude sickness that are specifically adapted to Chinese and Asian populations. 
"Previously, although acetazolamide had already been used internationally for the prevention of acute mountain sickness, China had long lacked an NMPA-approved acetazolamide formulation supported by rigorous clinical trials. Furthermore, the existing international formulations were short-acting tablets requiring multiple daily doses, and no drugs with the relevant indication were available on the domestic market for an extended period," said Luobu Gesang.
The sustained-release capsule approved this time not only fills this critical gap but also optimizes the dosage form, providing more reliable and convenient medication protection for the physical health and life safety of people entering high-altitude areas, he added.
Clinical trials showed that, compared with the placebo group, the incidence of acute mountain sickness in the medication group was significantly reduced, with the incidence of moderate-to-severe acute mountain sickness decreasing by 14.6 percent, according to the report.
Related research has been published in the international flagship journal of high-altitude medicine, High Altitude Medicine & Biology.
Global Times

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